Our Fertility Blog

Our Conceiving Journey

Day 2 Menopur ,Follistim & Lupron

Thursday, May 17, 2012

Tonight I add the Lupron to my nightly regimen.  Since Pete was working late I went ahead and decided to do the shots myself again.  I like to get it over with instead of waiting, even if I have to do it myself.

I am taking 20 units of Lupron.  I mixed the 12.5 units of Lupron with 2ml of the mixing agent.  The Lupron syringe is very small 8mm long and a 31gauge needle.  These type of needles are used for insulin.  Even though this needle is very thin it does not go into the skin smoothly.  This is because I have to fill the syringe with the same needle that goes into my stomach.  So when you are sticking something twice the second time is not as smooth.

Below is a re-cap description of each medicine

Menopur 300IU -  is a highly purified preparation of naturally derived gonadotropins, called hMG. Menopur contains equal amounts (75 IUs) of 2 kinds of hormonal activity: follicle-stimulating hormone (FSH), which helps stimulate egg production; and luteinizing hormone (LH), which helps the eggs mature and release (ovulate).

Follistim 300IU – is a recombinant (synthetic) version of human follicle stimulating hormone (FSH). It is indicated for the development of multiple follicles during ovulation for patients having assistance in reproduction.

Lupron 20units -the first fertility drug that most women use in an IVF cycle is Lupron. Lupron causes the pituitary gland to release high amounts of FSH and LH (luteinizing hormone) for several days until its stores are depleted. Since continued use of Lupron prevents the pituitary gland from producing new supplies of FSH and LH, the amount of these hormones being released per day becomes very low after 7 to 10 days. The goal that we achieve with Lupron is to ensure that blood levels of LH are low during the last few days of follicle growth, since we know that high levels of LH can lead to poor egg quality and stimulate progesterone production by the ovaries. A premature rise in progesterone may cause inappropriate maturation of the uterine lining and lead to a lesser chance of embryo implantation.

, , , ,

Leave a Reply